Division of Clinical Pathology

Clinical Pathology Care, Research & Education

The Division of Clinical Pathology, which includes Laboratory and Transfusion Medicine, is comprised of over 80 faculty members who actively participate in the Beth Israel Deaconess Medical Center (BIDMC) mission of clinical excellence, research and education. Faculty members oversee a broad range of clinical testing sections that include Clinical Chemistry, Clinical Microbiology, Cytogenetics and Genomics, Flow Cytometry, Hematology/coagulation, Hematopathology, HLA, Molecular and Precision Diagnostics, Point of Care testing, and Transfusion Medicine. In addition, our faculty are at the cutting edge of discoveries in clinical pathology, enabling our physician colleagues to provide the most advanced, comprehensive set of treatment options to patients.

The laboratories are state of the art provide testing, and the division provides consultative services for BIDMC and affiliated BILH network hospitals. The laboratories are CLIA approved and accredited by the College of American Pathologists (CAP), the Association for the Advancement of Blood and Biotherapies (AABB), and the American Society for Histocompatibility and Immunogenetics (ASHI). Overall, our laboratories perform over 8 million tests annually and we employ more than 450 laboratory professionals.

Call 617-667-3648

More About the Division

Care & Services

We provide a wide range of pathology services and procedures in our state-of-the-art laboratories.

Clinical Chemistry Lab

Clinical chemistry is a comprehensive laboratory, performing well over 100 different assays. The scope of activities include:

  • Automated immunoassays for endocrinology and tumor markers
  • Highly automated instrumentation, allowing the simultaneous quantitation of dozens of chemical constituents of blood
  • Immunoassays for hepatitis and related serologies
  • Protein electrophoresis and immunofixation electrophoresis with interpretation
  • Therapeutic drug monitoring and toxicology
  • Rapid diagnostic testing, including blood gas analysis
Clinical Microbiology Lab

Clinical Microbiology provides a broad array of diagnostic tests used for the diagnosis of infections by bacteria, viruses and parasites. The full-service laboratory manages:

  • Gram stains
  • Automated blood culture testing
  • Automated molecular diagnostic testing for bacterial and viral pathogens
  • MALDI-TOF testing
  • Antibiotic susceptibility testing
Cytogenetics Lab

The Cytogenetics Laboratory provides chromosome analysis, fluorescence in situ hybridization (FISH) and oligo-SNP chromosomal microarray for constitutional disorders and acquired neoplastic disorders. In addition, the laboratory can establish cell cultures to be sent out for molecular testing.

The Cytogenetics Laboratory also performs chromosome breakage analysis for Fanconi Anemia. For providers within the BILH network, please find additional information about this service in the Epic procedure catalog. For providers outside the BILH network, please refer to the links below to access additional information about sample submission and the test requisition.

For more information, email Annie Cheng or call 617-667-1456.

Hematopathology
Histocompatibility/Immunogenetics Laboratory

The Histocompatibility/Immunogenetics laboratory is responsible for histocompatibility testing for solid organ transplant recipients and their donors. Current transplant programs this laboratory supports include cardiac, kidney/pancreas, and liver transplant.

Additionally, the laboratory is responsible for histocompatibility testing of hematology/oncology patients required to manage platelet transfusion refractoriness. Other test offerings include disease association HLA testing (e.g., B27 for ankylosing spondylitis).

Flow Cytometry Lab

We offer state-of-the-art Flow Cytometry at BIDMC. The technology aids in the diagnosis and monitoring of acute leukemia, lymphoma, and many other hematologic disorders as well as immune cell monitoring in patients with suppressed immune systems. Availability of on-site testing allows rapid and more comprehensive testing, reducing turnaround time and facilitating seamless patient management.

Hematology Lab

The Hematology Laboratory is a full-service laboratory that performs:

  • Automated and manual blood counts and differential counts on white blood cells
  • Hemoglobin Electrophoresis with interpretation
  • Platelet aggregation studies with interpretation
  • Routine and reference coagulation testing with interpretation
  • Urinalysis
Blood Bank

The blood bank and Transfusion Medicine service provide routine and extended diagnostic testing for the varied and complex patient population cared for by BIDMC clinicians. Our faculty are available 24/7 to provide clinical consultations for transfusion management of transplant, trauma, neonatal, and obstetrical patients. The blood bank maintains a robust inventory of blood products, including:

  • Cryoprecipitate
  • Packed red cells
  • Plasma
  • Platelets
Education & Training

We are committed to equipping the next generation of clinical pathologists with the tools they need to provide high-quality, compassionate care to their patients. Our education and training opportunities include electives, residencies and fellowships.

Research

Our research team is at the leading edge of discoveries in clinical pathology, enabling our physicians to provide the most advanced, comprehensive set of treatment options to patients.