Clinical Trials at BIDMC
Review our current research studies.
Rheumatology Research
Rheumatology Research
The Division of Rheumatology and Clinical Immunology at BIDMC provides leading-edge, compassionate care to patients living with rheumatic diseases. The Division is dedicated to providing the highest quality of care to patients and advancing the field. Clinicians are actively engaged in innovative research in rheumatology and clinical immunology and are training the next generation in medicine through an ACGME-accredited Fellowship in Rheumatology for physicians interested in academic and research careers.
Investigations are supported by highly competitive grants from the National Institutes of Health, the Department of Defense, and additional funding from foundations and pharmaceutical companies. Present funding exceeds 3.0 million dollars annually.
Rheumatology Laboratory
The Rheumatology Division has an active basic and clinical research program in the field of Systemic Lupus Erythematosus (SLE) headed by Dr. George Tsokos.
- Adamopoulos Lab: Led by Iannis Adamopoulos, DPhil, this lab studies the interface between the skeletal and immune systems, a newly emerging area of research called “osteoimmunology.”
- Tsokos Lab: Headed by Dr. George Tsokos, this lab uses a broad range of research approaches, including lupus-prone mice, genetically engineered mice, metabolomics, RNA sequencing and single cell sequencing, and bioinformatics.
Publications
Our researchers have authored numerous studies and papers over the years.
More About Rheumatology Research
Federation of Clinical Immunology Societies (FOCIS) Center
The BIDMC FOCIS Center of Excellence aims to promote interdisciplinary clinical immunology at BIDMC by developing clinical research activities that cross established disciplines; establish training and scientific forums that encourage collaborative activities among BIDMC faculty and other FCE faculty; promote attendance of FOCIS annual meeting and other sponsored activities by faculty and trainees.
Division of Rheumatology Research
Research activities within the Division include:
- Study of immune cell signaling events in patients with systemic lupus erythematosus
- Study of regulatory T cells in patients with autoimmune diseases
- Study of Il-17 producing cells in autoimmune diseases
- Study of mechanisms that are involved in the development of lupus nephritis
- Studies to understand the propensity of patients with lupus to infections
- Study of the role of complement in the expression of tissue damage
- Preclinical studies in lupus-prone mice and other engineered mice to characterize disease mechanisms and to develop novel therapeutics
Research at BIDMC
Our culture of collaboration and innovation guides scientific discoveries that are helping to transform medical care.
Division of Rheumatology & Immunology
The Division of Rheumatology and Immunology, part of the Department of Medicine, offers world-class patient care, research programs, and education and training opportunities.
