Plastic and Reconstructive Surgery Research
Research Team, Projects and Publications
Research Team
- Bernard Lee, MD, MBA, MPH, FACS, Chief, Division of Plastic and Reconstructive Surgery
- Samuel Lin, MD, MBA, Program Director, Aesthetic Plastic Surgery Fellowship
- Dhruv Singhal, MD, Director, Lymphatic Surgery, Plastic Surgery
- Eugene Fukudome, MD, Faculty, Plastic Surgery
- Donald Morris, MD, Faculty, Plastic Surgery
- Sumner Slavin, MD, Program Director, Aesthetic Plastic Surgery Fellowship
- Adam Tobias, MD, Program Director, Breast Reconstructive Surgery Fellowship
- Joseph Upton, MD, Program Director, Hand/Microsurgery Fellowship
- Arriyan S. Dowlatshahi, MD, Faculty, Plastic Surgery and Orthopaedic Surgery
- Christine Kang, MD, MPH
- Darya Kazei, MD
- Diana del Valle, MD
- Marek Paul, MD
- Carolina Manrique, MD
If you are interested in applying to join our team as a Research Fellow or Research Intern, please email Dr. Carly Comer.
Basic Research Projects
- Electrochemical Activation and Inhibition of Neuromuscular Systems through Modulation of Ion Concentrations with Ion-Selective Membranes
- Peripheral Circulation Detection and Therapeutic Targeting of Progenitor Stem Cells in Breast Cancer Patients
- Suture-less Anastomosis Using Silk Protein Biomaterials for Coupler Fabrication
- Perforator Identification Using Near-Infrared Imaging (NIR):
- Near-Infrared Imaging for Intra-operative Assessment of Perfusion in Vascularized Bone Flaps
- Spatial Frequency Domain Imaging to Effectively Monitor Viability of Composite Tissue Facial Flaps
- Clinical Pilot Study Using Spatial Frequency Domain Imaging to Assess Oxygenation of Perforator Flaps during Breast Reconstructive Surgery
Clinical Research Projects
Clinical Outcomes & Patient Satisfaction after Breast Cancer Reconstruction
- Evaluation of Breast Reconstruction Outcomes in an Academic Medical Center
- Outcomes of a Microsurgical Breast Reconstruction (DIEP Flap) Program
- Shared Decision Making increase Patient Satisfaction in Breast Cancer Reconstruction
- Impact of Complications on Patient Satisfaction in Breast Reconstruction
- Health Quality Outcomes of Breast Reconstruction in the Elderly
- Breast Cancer Recurrence Following Post Mastectomy Reconstruction
- Outcomes Following Breast Reconstruction Using the National Surgical Quality Improvement Program (NSQIP) Database
- Cost Analysis in Breast Reconstruction
- Autologous Fat Grafting in Breast Reconstruction
- Evaluation of Prophylactic, Risk Reducing Mastectomy and Breast Reconstruction
- Clinical Outcomes after Nipple Sparing Mastectomy and Breast Reconstruction
Evaluation of Outcomes in Cosmetic Breast Surgery
- Clinical Outcomes and Patient Satisfaction with Cosmetic Breast Augmentation Surgery (Breast Implant)
- Clinical Outcomes and Patient Satisfaction with Cosmetic Breast Mastopexy (Breast Lift)
Use of Acellular Dermal Matrices in Breast Plastic Surgery
- Long-term Clinical Outcomes of the Upper Extremity
- Management and Rehabilitation of the Upper Extremity
- Replantations
- Studies in Complex Hand Reconstruction
- The Congenital Hand
- Traumatic Upper Extremity Injuries
- Vascular Malformations
- Real-time Intraoperative Computed Tomography Monitoring of Fracture Reduction
- Outcomes Following Surgery for Skin Cancer of the Head and Neck
- Evaluation of the Nasal Airway Using an Acoustic Rhinometer
Selected Publications
Ashitate Y, Lee BT*, Laurence RG, Lunsford E, Hutteman M, Oketokoun R, Choi HS, Frangioni JV. Intraoperative prediction of post-operative flap outcome using the near-infrared fluorophore methylene blue. Ann Plast Surg 2012 Mar 6 [Epub ahead of print].
Ayeni OA, Ibrahim AM, Lin SJ, Slavin SA. Acellular dermal matrices in breast surgery: tips and pearls. Clin Plast Surg 2012;39:177-186.
Caterson SA, Fox SE, Tobias AM, Lee BT. Functional MRI to evaluate “sense of self” following perforator flap breast reconstruction. PLoS One 2012 (in press).
Chen Y, Liang F, Gerstle T, Lee BT. Use of a novel laser projection grid to assess symmetry in breast surgery. Plast Reconstr Surg 2012; 130(1):231-3e.
de Blacam C, Ogunleye AA, Momoh AO, Colakoglu S, Tobias AM, Sharma R, Houlihan MJ, Lee BT. High body mass index and smoking predict morbidity in breast cancer surgery: a multivariate analysis of 26,988 patients from the NSQIP database. Ann Surg 2012; 255(3):551-5.
de Blacam C, Colakoglu S, Momoh AO, Lin SJ, Tobias AM, Lee BT. Early experience with barbed sutures for abdominal closure in DIEP flap breast reconstruction. ePlasty 2012;12:e24.
Gioux S, Mazhar A, Lee BT, Cuccia DJ, Stockdale A, Oketokoun R, Ashitate Y, Durr N, Durkin AJ, Tromberg BJ, Frangioni JV. Preclinical and clinical validation of a novel oxygenation imaging system. Proc SPIE 2012 (in press).
Hadad I, Ibrahim AM, Lin SJ, Lee BT. Augmented SIEA flap after ligation of bilateral inferior epigastric arteries and DIEP vessels. J Plast Reconstr Aesthet Surg. Oct 6 2012. PMID: 23047181.
Ibrahim AM, Rabie AN, Lee BT, Lin SJ. Intraoperative CT: A teaching tool for the management of complex facial fracture fixation in surgical training. J Surg Educ 2011;68:437-441. PMID: 22135829.
Ibrahim AM, Ayeni OA, Hughes KB, Lee BT, Slavin SA, Lin SJ. Acellular Dermal Matrices in Breast Surgery: A Comprehensive Review. Accepted, Ann Plast Surg.
Ibrahim AM, Gerstle TL, Rabie AN, Song YA, Melik R, Han J, Lin SJ. Nanotechnology in Plastic Surgery. Plast Reconstr Surg. Aug 8 2012. PMID: 22878482.
Ibrahim AM, Rabie AN, Kim PS, Medina MA, Upton J, Lee BT, Lin SJ. Static Treatment Modalities in Facial Paralysis: A Review. Accepted, J Reconstr Microsurg.
Ibrahim AMS, Rabie AN, Kim PS, Upton J, Lee BT, Lin SJ. Vasopressors and reconstructive flap perfusion: a meta-analysis comparing the effects of various drugs. Ann Plast Surg 2013 (in press).
Izadpanah A, Sinno H, Vorstenbosch J, Lee BT, Lin SJ. Thigh deformity after massive weight loss: an assessment of health state study. Ann Plast Surg 2012 (in press).
Kasper EM, Ridgway EB, Rabie A, Lee BT, Chen C, Lin SJ. Staged scalp soft tissue expansion before delayed allograft cranioplasty: a technical report. Neurosurg 2012; 71 (1 Suppl Operative);15-21.
Khansa I , Momoh AO, Patel PP, Nguyen JT, Miller MJ, Lee BT. Fat Necrosis in Autologous Abdominal Based Breast Reconstruction: A Systematic Review Accepted: Plastic and Reconstructive Surgery.
Ko JH, Kim PS, O’Shaughnessy KD, Kuiken TA, Dumanian GA. A Quantitative Evaluation of Gross Versus Histologic Neuroma Formation in a Rabbit Forelimb Amputation Model: Potential Implications for the Operative Treatment and Study of Neuromas. Journal of Brachial Plexus and Peripheral Nerve Injury 2011, 6:8.
Lee DT, Jenkins NL, Anastasopulos AJ, Volpe AG, Lee BT, Lalikos JF. Transdermal scopolamine and perioperative anisocoria in craniofacial surgery: a report of three patients. J Craniofac Surg 2012 (in press).
Lee BT, Duggan MM, Keenan MT, Kamatkar S, Quinlan RM, Hergrueter CA, Hertl MC, Shin JH, Truppin NB, Chun YS, and the Massachusetts Board of Registration in Medicine Expert Panel on Immediate Implant Based Breast Reconstruction following Mastectomy for Cancer. Commonwealth of Massachusetts Board of Registration in Medicine expert panel on immediate implant-based breast reconstruction following mastectomy for cancer: executive summary, June 2011. J Am Coll Surg 2011; 213(6):800-5.
Lin SJ. Complications in Facial Plastic Surgery. Invited Book Review, Plastic and Reconstructive Surgery.
Lin SJ. Take Two and Text Me in the Morning: optimizing clinical time with a short messaging system. Plast Reconstr Surg 130: 50-52, 2012.
Momoh AO, Kelley BP, Diaz-Garcia RJ, Kulkarni AR, Kozlow JH, Bullocks JM, Lee BT. An alternative mucosal flap for nasal lining: the superior labial artery mucosal flap – an anatomic study. J Craniofac Surg 2012 (in press).
Momoh AO, Colakoglu S, de Blacam C, Gautam S, Tobias AM, Lee BT. Delayed autologous breast reconstruction after postmastectomy radiation therapy: is there an optimal time? Ann Plast Surg 2012;69(1):14-8.
Momoh AO, Colakoglu S, de Blacam C, Curtis MS, Lee BT. The forked liposuction cannula: a novel approach to the correction of cicatricial contracture deformities in breast reconstruction. Ann Plast Surg 2012;69(3):256-9.
Momoh AO, Colakoglu S, de Blacam C, Yueh JH, Lin SJ, Tobias AM, Lee BT. The impact of nipple reconstruction on patient satisfaction in breast reconstruction. Ann Plast Surg 2012;69(4):389-93.
Izadpanah A, Sinno H, Vorstenbosch J, Lee BT, Lin SJ. Thigh deformity after massive weight loss: an assessment of health state study. Ann Plast Surg 2012 (in press).
Nguyen JT, Ashitate Y, Buchanan IA, Ibrahim AM, Gioux S, Patel PP, Frangioni JV, Lee BT. Bone flap perfusion assessment using near-infrared fluorescence imaging. J Surg Res. May 24 2012. PMID: 22664132.
Nguyen JT, Ashitate Y, Buchanan IA, Ibrahim AM, Gioux S, Patel PP, Frangioni JV, Lee BT. Face transplant perfusion assessment using near-infrared fluorescence imaging. J Surg Res 2012 Oct; 177(2): e83-8. PMID: 22572616.
Nguyen JT, Buchanan IA, Patel PP, Aljinovic N, Lee BT. Intercostal Neuroma as a Source of Pain after Aesthetic and Reconstructive Breast Implant Surgery. Accepted: The Journal of Plastic, Reconstructive & Aesthetic Surgery.
Ogunleye AA, de Blacam C, Curtis MS, Colakoglu S, Tobias AM, Lee BT. An analysis of delayed breast reconstruction outcomes as recorded in the American College of Surgeons National Surgical Quality Improvement Program. J Plast Reconstr Aesthet Surg 2012; 65:289-94.
Patel PP, Ibrahim AM, Zhang J, Nguyen JT, Lin SJ, Lee BT. Accessory breast tissue. Eplasty 2012;12:ic5. PMID: 22536461.
Patel PP, Ibrahim AM, Zhang J, Nguyen JT, Lin SJ, Lee BT. A Jaw Dropping Predicament. Accepted, Eplasty.
Rabie AN, Ibrahim AM, Kim PS, Medina MA, Upton J, Lee BT, Lin SJ. Dynamic Rehabilitation of Facial Nerve Injury: A Review of the Literature. Accepted, J Reconstr Microsurg.
Rabie AN, Chang J, Ibrahim AM, Lee BT, Lin SJ. Use of Tragal Cartilage Grafts in Rhinoplasty: An Anatomic Study and Review of the Literature. Accepted, Ear Nose Throat J.
Rabie A, Ibrahim AM, Lee BT, Lin SJ. Use of intraoperative computed tomography in complex facial fracture reduction and fixation. J Craniofac Surg 2011;22:1466-1467. PMID: 21772153.
Silvestre J, Bess CR, Nguyen JT, Ibrahim AM, Patel PP, Lee BT. Evaluation of Wait Times for Patients Seeking Cosmetic and Reconstructive Breast Surgery. Accepted, Ann Plast Surg.
Singhal D, Momoh AO, Colakoglu S, Qureshi A, Tobias AM, Lee BT. Intra-muscular perforator dissection with the hydrodissection technique. J Reconstr Microsurg 2012 Oct 4. [Epub ahead of print].
Singhal D, Fanzio PM, Lee ET, Chang CJ, Lee BT, Cheng MH. High volume hydrodissection: increasing the safety and efficiency of perforator dissection. Ann Plast Surg 2012 (in press).
Sinno H, , Tahiri Y , Christodoulou G, Izadpanah A, Thibaudeau S, Williams BH, Slavin SA, Lin SJ. The Impact of Living with Severe Lower Extremity Lymphedema: A Utility Outcomes Score Assessment. Accepted, Ann Plast Surg.
Sinno H, Izadpanah A, Thibaudeau S, Christodoulou G, Lin SJ, Dionisopoulos T. An objective assessment of the perceived quality of life of living with bilateral mastectomy defect. Breast. 2012 Jul 31. [Epub ahead of print]
Sinno HH, Ibrahim AM, Izadpanah A, Thibaudeau S, Christodoulou G, Tahiri Y, Slavin SA, Lin SJ. Utility Outcome Assessment of the Aging Neck following Massive Weight Loss. Otolaryngol Head Neck Surg 2012 Jul;147(1):26-32. PMID: 22378827.
Slavin SA, Lin SJ. Use of Acellular Dermal Matrices in Aesthetic Breast Surgery. Plast Reconstr Surg. 2012 Nov;130(5 Suppl 2):70S-85S.
Song YA, Rabie AN, Ibrahim A MS, Moses D, Tan A, Han J, Lin SJ. Electrochemical Activation and Inhibition of Neuromuscular Systems with Modulation of Ion Concentrations Using Ion-Selective Membranes. Nature Materials 2011 Oct 23;10(12):980-6.
Song YA, Ibrahim AM, Rabie AN, Han J, Lin SJ. Electrical Interfaces in Biomedical Systems: Fundamentals and Applications in Neural Prosthetics and Neural Engineering. Invited Submission, Biotechnol Genet Eng Rev. September 2012.
Taghinia Ah, Upton J. Index finger pollicization. J Hand Surg Am. 2011;36(2):333-9.
Talbot S., Kerstein D., Jacobs L., Upton J. Case Report Postoperative use of the NormaTec Pneumatic compression Device in Vascular Anomalies. ePlasty. 2012;12:e6.
Upton J, Taghinia A. Special considerations in vascular anomalies: Operative management of upper extremity lesions. Clin Plast Surg. 2011;38(1): 143-51.
*Co-first author on publication.