Brain Health Research & Clinical Trials
About Our Scientific Approach
The Sadhguru Center uses scientific approaches to integrate medical and contemplative sciences to improve brain health and general well-being. Our team conducts research that employs both clinical and mindfulness-based interventions such as multimodal intraoperative general anesthesia, and opioid-sparing effective pain control in the postoperative period to improve post-operative outcomes, particularly related to cognitive decline and delirium that often occur in aged patients.
The Center's work will provide insight into how consciousness, cognition and compassion are aided by meditative practices. With the aid of enhanced functional MRI (fMRI) tools developed over the last decade, there has been a substantial increase in research conducted on how meditative practices change the brain size and neural network connectivity. There are ongoing clinical studies conducted in the Center that explore how meditative practices affect consciousness and cognition, as well as emotional well-being. Work is also underway to create a database of people who have integrated meditation into their daily routine with the goal of evaluating long-term benefits of regular meditation on emotional well-being. Combined, these approaches will help elucidate how meditative practices influence the potential physiological changes.
Study by Upadhyay et al. (2022) finds Inner Engineering Online (IEO) had significant positive effect on employee wellbeing and positive organizational behavior. Large-scale genomic study by Chandran et al. (2021) reveals robust activation of the immune system following an advanced meditation program. Study by Azimaraghi et al. (2022) found that deep levels of benzodiazepine-induced sedation were associated with a fewer number of delirium-free days after extubation. Study by Shanker et al. (2021) finds successful use of a total intravenous anesthesia (TIVA)-based MMGA strategy for cardiac surgery.
Yoga & Meditation: Impact on Well-being
Yoga & Meditation: Neuro-Physiology
Anesthesia: Perioperative Neurocognitive Disorders
Cardiac Anesthesia