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More on Exercise

Posted 1/23/2010

Posted in

As I do virtually every morning, unless I have a very early meeting or flight to catch or some other solid excuse, I got up and went to the gym this morning. It is Saturday so the time pressures are reduced--but the flip side of that is that it would have been possible to go back to sleep or return to bed with the newspaper and coffee. In spite of my obsessive commitment to exercise, I never really enjoy it. Years ago, when I trained for and ran a marathon, I waited in vain for the lauded "runners' high." It is all about self-discipline, my hope that the data re exercise and recurrence is correct, and my unwillingness to give up food.

I have written several times before about the apparent benefit of regular exercise in decreasing the risk of recurrence. There have been a continuing series of studies supporting this fact. A new meta-analysis from Speck and colleagues examined all English language studies and found the following:

An update of controlled physical activity trials in cancer survivors: a systematic review and meta-analysis

Rebecca M. Speck & Kerry S. Courneya & Louise C. Mâsse & Sue Duval & Kathryn H. Schmitz Received: 7 September 2009 / Accepted: 26 November 2009 # Springer Science+Business Media, LLC 2009

Abstract

Introduction Approximately 11.1 million cancer survivors are alive in the United States. Activity prescriptions for cancer survivors rely on evidence as to whether exercise during or after treatment results in improved health outcomes. This systematic review and meta-analysis evaluates the extent to which physical activity during and post treatment is appropriate and effective across the cancer control continuum.

Methods A systematic quantitative review of the English language scientific literature searched controlled trials of physical activity interventions in cancer survivors during and post treatment. Data from 82 studies were abstracted, weighted mean effect sizes (WMES) were calculated from 66 high quality studies, and a systematic level of evidence criteria was applied to evaluate 60 outcomes. Reports of adverse events were abstracted from all studies.

Results Quantitative evidence shows a large effect of physical activity interventions post treatment on upper and lower body strength (WMES=0.99 & 0.90, p<0.0001 & 0.024, respectively) and moderate effects on fatigue and breast cancer-specific concerns (WMES=−0.54 & 0.62, p=0.003 & 0.003, respectively). A small to moderate positive effect of physical activity during treatment was seen for physical activity level, aerobic fitness, muscular strength, functional quality of life, anxiety, and self-esteem. With few exceptions, exercise was well tolerated during and post treatment without adverse events.

Conclusions Current evidence suggests many health benefits from physical activity during and post cancer treatments. Additional studies are needed in cancer diagnoses other than breast and with a focus on survivors in greatest need of improvements for the health outcomes of interest.

Keywords Exercise . Cancer . Survivorship . Adults .

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