Program in Human Basal Ganglion Research

The Program in Human Basal Ganglion Research is a division of the Laboratory of Integrative Neurobiology. Research examines the chemical neuroanatomy of the human basal ganglion system, both in normal brains, and in the brains of people who have died with movement disorders. Projects examine both the central catecholaminergic system in Parkinson's disease, as well as the chemical compartmentalization of the human striatum. We are particularly interested in correlating the changes that occur in basal ganglion organization with the widely varied clinical courses of patients with movement disorders, to determine the role played by specific circuits in movement control and its dysfunction.

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