beth israel deaconess medical center a harvard medical school teaching hospital

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Dr. Mark L. Zeidel

Mark Zeidel, MD is the Herman Ludwig Blumgart Professor of Medicine at Harvard Medical School, Physician-in-Chief and Chairman of the Department of Medicine at the Beth Israel Deaconess Medical Center. He is a widely recognized scientist, clinician and teacher, known for his research in the area of epithelial biology and water transport.

Zeidel, has spent the past 12 years at the University of Pittsburgh School of Medicine, first as chief of the renal and electrolyte division of the Department of Medicine, and since 1999, as the Jack D. Myers Professor and Chair of the Department of Medicine. A summa cum laude graduate of Yale College in 1976, he received an MD degree from Columbia University College of Physicians and Surgeons in 1980. He trained in internal medicine and nephrology at Brigham and Women's Hospital, and was chief of the renal section of the West Roxbury VA and Assistant Professor of Medicine at Harvard before moving to Pittsburgh in 1993.

Zeidel is the recipient of National Institutes of Health funding for his outstanding research in the area of epithelial biology and water transport during his tenure as chair at Pittsburgh. Dr. Zeidel's research focuses on mechanisms of water and small molecule flow across biological membranes and on mechanisms of epithelial injury. The first measurements of intracellular pH in renal cells, the discovery that atrial natriuretic peptide and related peptides (such as brain natriuretic peptide) function by blocking sodium channels in collecting duct cells, the reconstitution and biophysical definition of the function of aquaporin water channels and the molecular definition of how membranes can be impermeable to gases and water are a few of the major research findings in his laboratories. His research has received continuous funding by the NIH for over 20 years. He has been recognized by his peers for numerous accomplishments, including elected membership in the American Society of Clinical Investigation and the Association of American Physicians.

Publications