Taxol Schedules Equally Effective
Many of us have received Taxol as part of our chemotherapy regimen. You likely know that it is generally given in one of two ways: either 4 times in the Dose Dense regimen (meaning an infusion every two weeks), or a smaller dose weekly for 9 or 12 weeks. The total amount of Taxol given is the same, but the dose can vary a lot depending on the schedule. This study, just presented at ASCO, suggests that the two schedules are equally effective, and the smaller weekly doses are much easier to take--fewer side effects. The disadvantage is that one has to show up for chemo every week, but many of us would choose the increased visits for fewer side effects.
Here is the beginning of the story from Patient Net and then a link to read more:
.. .. .. ....Two Commonly Used Paclitaxel Chemotherapy Schedules are Equally Effective for Early-Stage Breast Cancer, but One Has Fewer Side Effects
..Women with higher-risk, early-stage breast cancer who received weekly chemotherapy with paclitaxel (Taxol) after surgery as part of a clinical trial lived for the same amount of time without the cancer returning as those who received higher doses of the same drug every two weeks (known as dose-dense therapy). However, the researchers found that the women who received chemotherapy every week experienced fewer and less serious treatment-related side effects.
Chemotherapy is the use of drugs to kill cancer cells, which work by stopping the cancer cells’ ability to grow and divide. Drugs like paclitaxel are often given after surgery for breast cancer to kill any cancer cells that may remain in the body. Paclitaxel is usually given to patients either weekly or every two weeks, at a higher dose. Although doctors currently use both treatment schedules, this is the first time researchers have looked at whether they have different results for patients